MSAT Specialist

Job Title: Specialist - MSAT

Career Level: C

About Singapore ADC Site:

Be part of history in the making. AstraZeneca is building its first biologics manufacturing campus in Singapore - a groundbreaking USD 1.5 billion investment that will serve as a global hub for innovation and excellence.

This innovative facility will deliver end-to-end Antibody-Drug Conjugate (ADC) capabilities with different manufacturing units/buildings in one campus:

• Small molecule- chemical API production
• Large molecule- monoclonal antibody manufacturing
• Conjugation
• Fill-and-finish operations, including sterile filling and lyophilization
• Final secondary packaging

The campus will be equipped with innovative digital and automation infrastructure, enabling autonomous manufacturing powered by artificial intelligence. In addition, it will be designed for carbon neutrality, embedding sustainability into every aspect of operations and setting a new benchmark for environmentally responsible biologic's manufacturing.

In Manufacturing Science and Technology Team, we are looking for passionate individuals with relevant experience who thrive in dynamic environments and bring a "make-it-happen" attitude. Joining us means contributing to a project that will not only transform AstraZeneca's global supply chain but also advance life-changing medicines for patients everywhere.

If you're ready to shape the future of biologics and be part of a once-in-a-generation project, we want you on our team.

Introduction to role:

Are you ready to apply scientific rigor and data-driven insight to strengthen manufacturing processes that deliver life-changing medicines to patients faster? Do you thrive at the intersection of technology transfer, validation, and real-time process monitoring, turning complex data into clear action?

As an MSAT Specialist, you will reinforce process robustness across biologics, API, and fill-finish operations, directly shaping consistent product quality and reliable supply. You will drive process validation, control strategy implementation, and continued process verification, using evidence-based decisions to keep our facilities inspection-ready and our product supply on time.

Working within a collaborative technology transfer team, you will partner closely with Operations, Quality, Supply Chain, Engineering, and global technical experts. You will help translate new and complex modalities into scalable, compliant manufacturing, using Lean methods and digital tools to accelerate how we deliver therapies with speed and confidence.

Accountabilities:

• Technology Transfer and Validation: Develop, review, and execute technology transfer plans, validation documentation, risk assessments, control strategies, and lifecycle technical records to enable robust scale-up and scale-out.
• Process Control and Monitoring: Implement and maintain control strategies by monitoring critical quality attributes, critical process parameters, and process performance indicators to sustain a state of control.
• Data Analytics and Trend Management: Analyze process data and manufacturing trends to identify risks, deviations, and improvement opportunities; call out signals early to protect supply and compliance.
• Technical Investigations and CAPA: Lead and contribute to root cause analysis, risk assessments, and implementation of corrective and preventive actions that resolve issues and prevent recurrence.
• Regulatory Readiness and Submissions: Prepare technical documentation, data summaries, and responses to support inspections and regulatory filings related to process performance and validation.
• Multi-Functional Technical Input: Provide practical guidance across manufacturing and packaging processes to meet internal and external standards while improving yield, throughput, and reliability.
• Issue Resolution and Customer Engagement: Resolve technical issues within your area and facilitate multi-functional problem-solving for complex challenges with clear, timely communication.
• Systems, Equipment, and Compliance: Apply knowledge of manufacturing systems, equipment, and regulatory requirements to drive compliant, efficient operations and continuous improvement.
• Knowledge Sharing and Standardization: Share lessons learned and standard methodologies to build team capability and promote consistent ways of working across sites and partners.
• Change Execution and Risk Mitigation: Execute approved process changes and risk actions, and implement new technologies or methodologies to enhance robustness and efficiency.
• Alignment to Priorities: Align technical activities with operational, quality, and business priorities to support reliable supply and strategic objectives.
• External Collaboration: Partner with suppliers, engineers, and external customers to investigate issues and implement agreed solutions that strengthen the end-to-end value chain.
• Technical Communication: Prepare and present technical findings and recommendations for both technical and non-technical audiences, ensuring clarity and decision-making agility.
• Digital Adoption: Support the adoption of digital solutions, monitor their effectiveness, and provide feedback to improve deployment and impact.

Essential Skills/Experience:

• Degree in technical or scientific field OR Technical/Associate/Vocational diploma with equivalent experience
• Relevant experience in regulated manufacturing environments
• Demonstrated expertise in manufacturing or packaging operations
• Proven ability to resolve complex technical issues
• Practical knowledge of GMP, SHE, SOPs, compliance frameworks
• Hands-on experience with continuous improvement strategies and tools
• Understanding of manufacturing and engineering landscapes
• Proficiency in engaging diverse audiences with clear and effective communication.

Desirable Skills/Experience:

• Hold or pursue recognised professional certification
• Committed to formal technical development
• Understanding interactions of machinery / equipment, components/ materials, and process performance
• Awareness of supply chain operations with process optimization

When we put unexpected teams in the same room, we unleash bold thinking with the power to inspire life-changing medicines. In-person working gives us the platform we need to connect, work at pace and challenge perceptions. That's why we work, on average, a minimum of three days per week from the office. But that doesn't mean we're not flexible. We balance the expectation of being in the office while respecting individual flexibility. Join us in our unique and ambitious world.

Why AstraZeneca:

Here, you will join a science-led, patient-focused company that pairs Lean ways of working with cutting-edge digital technologies to turn complex pipelines into reliable supply. We bring diverse experts together to solve real manufacturing challenges, invest in modern facilities and skills, and encourage people to take ownership while valuing kindness alongside ambition. You will have the freedom to lead, the support to grow, and the opportunity to see your technical decisions translate into safe, effective medicines reaching patients sooner.

Call to Action:

Step into this role to shape robust, compliant manufacturing and accelerate therapies to patients-take your next career leap with us today!

Date Posted

15-Oct-2026

Closing Date

28-Oct-2026

AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics. We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorization and employment eligibility verification requirements.