Manufacturing Senior Technician/ Technician

Title : Manufacturing Senior Technician/ Technician

GCL : C

Introduction to role

Be part of history in the making. AstraZeneca is building its first biologics manufacturing campus in Singapore - a groundbreaking USD 1.5 billion investment that will serve as a global hub for innovation and excellence.

This innovative facility will deliver end-to-end Antibody-Drug Conjugate (ADC) capabilities with different manufacturing units/buildings in one campus

• Small molecule- chemical API production

• Large molecule- monoclonal antibody manufacturing
• Conjugation
• Fill-and-finish operations, including sterile filling and lyophilization
• Final secondary packaging

The campus will be equipped with modern digital and automation infrastructure, enabling autonomous manufacturing powered by artificial intelligence. In addition, it will be designed for carbon neutrality, embedding sustainability into every aspect of operations and setting a new benchmark for environmentally responsible biologics' manufacturing.

We are looking for passionate individuals with relevant experience who thrive in dynamic environments and bring a "make-it-happen" attitude. Joining us means contributing to a project that will not only transform AstraZeneca's global supply chain but also advance life-changing medicines for patients everywhere.

If you're ready to shape the future of biologics and be part of a once-in-a-generation project, we want you on our team.

Accountabilities

• Safe and Compliant Manufacturing: Implement manufacturing activities in accordance with approved electronic batch records, SOPs, permits, cGMP, data-integrity, and Safety, Health and Environmental requirements; operate process equipment and control systems within approved ranges; identify, contain and call out deviations, alarms, unsafe conditions and quality risks; apply appropriate controls for hazardous chemicals, combustible materials, potent compounds and process hazards.
• Batch Execution and Equipment Readiness: Achieve manufacturing, quality and delivery goals by verifying equipment status, calibration, materials, labels, utilities and documentation before processing; perform transfers, sampling, cleaning and equipment changeover; complete contemporaneous and accurate manufacturing records and electronic entries to ensure traceability and right-first-time documentation
• Shift Coordination and Team Support: Support daily work allocation, production priorities, status reporting and effective shift handovers under the direction of the Shift Team Lead; take responsibility for personal development, build skills in new digital tools and technologies, and collaborate to drive digital adoption within the area.
• Quality and Investigation Support: Identify, contain and report process, equipment, documentation or material discrepancies; participate in investigations and root-cause analysis; draft analyses, recommendations and reports; support CAPAs, change controls, risk assessments, validation and inspection readiness while contributing to ongoing change-management. Operational Excellence: Perform first-line troubles-hooting and collaborate with
• Quality, Engineering, MS&T and Safety to resolve issues safely and minimize disruption; contribute to continuous improvement using lean and structured problem-solving tools to improve safety, quality, cycle time, yield, waste reduction, equipment reliability and operator effectiveness; support project delivery by analyzing requirements, agreeing action plans, tracking risks and communicating progress.
• Operational Readiness and Equipment Qualification: Support operational readiness activities including SOP development, batch record input, equipment setup, line readiness and material flow review; support FAT, SAT, commissioning, qualification and validation for manufacturing and containment equipment; support implementation, start-up and lifecycle management of key manufacturing systems and equipment.

Essential Skills/Experience

• Bachelor's degree or working towards a professional qualification, or High School/Technical/Associate/Vocational Diploma with equivalent experience.
• Demonstrated commitment to safety, quality, and delivery in a regulated manufacturing environment.
• A strong safety-first attitude, with awareness of operator safety, equipment safety, containment control and shopfloor usability.
• Strong written and verbal communication skills, with good attention to detail.

Desirable Skills/Experience

• Experience in pharma or biopharma GMP manufacturing.
• Hands-on experience in equipment trouble-shooting, fault diagnosis, and issue resolution in a GMP manufacturing environment.
• Good understanding of GMP documentation, deviation management, change control, CAPA, and equipment lifecycle management.
• Experience with operating Emerson DeltaV, Veeva QualityDocs, SAP, Siemens PLCs, etc.
• Experience in ADC, high containment, high potency, aseptic, or other highly controlled manufacturing environments.
• Exposure to manufacturing investigations, equipment reliability improvement, or production support projects.
• Experience with structured problem solving, root cause analysis, Lean Six Sigma, or reliability improvement tools.
• Strong cross-functional collaboration skills, with the ability to work effectively across Production, Engineering, Validation, QA, and SHE

When we put unexpected teams in the same room, we unleash bold thinking with the power to inspire life-changing medicines. In-person working gives us the platform we need to connect, work at pace and challenge perceptions. That's why we work, on average, a minimum of three days per week from the office. But that doesn't mean we're not flexible. We balance the expectation of being in the office while respecting individual flexibility. Join us in our unique and ambitious world.

Why AstraZeneca

Here you will help turn breakthrough science into medicines at scale using advanced digital tools, highly automated systems and disciplined Lean practices. We bring diverse experts together to solve hard problems, combining ambition with kindness and a strong focus on safety and sustainability. With a global network and significant investment in modern facilities, you'll gain exposure to varied technologies, learn from teams across the world, and build a long-term career while making a clear difference for patients and communities.

Call to Action

Step into a role where your precision and drive keep critical manufacturing running safely and on time-join us to build your capabilities, shape your impact and help deliver more medicines to patients, faster.

Date Posted

15-Oct-2026

Closing Date

28-Oct-2026

AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics. We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorization and employment eligibility verification requirements.